NSC-632839Band: www.medchemexpress.comInhibitor of the ubiquitin isopeptidases, inducing a rather unique apoptotic pathway including a Bcl-2-dependent but apoptosome-independent mitochondrial pathway with up-regulation of the BH3-only protein Noxa CAS No: 157654-67-6 Chemical…
BMS-8Band: www.medchemexpress.comNovel inhibitor of the PD-1/PD-L1 interaction by inducing PD-L1 dimerization through PD-1 interacting surface, binding at a hydrophobic cavity formed upon PD-L1 dimerization CAS No: 1675201-90-7 Chemical Name: 1--piperidine-2-carboxylic acid…
BMS-202Band: www.medchemexpress.comNovel inhibitor of the PD-1/PD-L1 interaction by inducing PD-L1 dimerization through PD-1 interacting surface CAS No: 1675203-84-5 Chemical Name: N-(2-{-amino}-ethyl)-acetamide TAK-242 Molecular Formula C₂₅H₂₉N₃O₃ Molecular Weight 419.52 CAS Numbers 1675203-84-5…
Shield-1Band: www.medchemexpress.comNovel cell permeable small molecule redulator of specific protein functions The Shield-1 ligand can simultaneously stabilizes and destabilizes a protein of interest depending on the amount of the ligand used within…
SAFit2Band: www.medchemexpress.comHighly selective inhibitor of the FK506-binding protein 51 (FKBP51)CAS No: 1643125-33-0 Chemical Name: (S)-((R)-3-(3,4-Dimethoxyphenyl)-1-(3-(2-morpholinoethoxy)phenyl)propyl) 1-((S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carboxylate LY2835219 Molecular Formula C46H62N2O10 Molecular Weight 802.99 CAS Numbers 1643125-33-0 Storage Condition 0°C (short term),…
SAFit1Band: www.medchemexpress.comHighly selective inhibitor of the FK506-binding protein 51 (FKBP51) Monomethyl auristatin E Molecular Formula C42H53NO11 Molecular Weight 747.87 CAS Numbers 1643125-32-9 Storage Condition 0°C (short term), -20°C (long…
AZD7762Band: www.medchemexpress.comA potent ATP-competitive checkpoint kinase inhibitorCAS No:860352-01-8 EPZ015666 Molecular Formula C17H19FN4O2S •HCl •H2O Molecular Weight 416.9 CAS Numbers 860352-01-8 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility…
AZD5363Band: www.medchemexpress.comAn orally bioavailable, selective and potent inhibitor of all PKB/AKT iso-formsCAS No:1143532-39-1 PKC412 Molecular Formula C19H21ClN6O2 Molecular Weight 428.92 CAS Numbers 1143532-39-1 Storage Condition 0°C (short term), -20°C (long…
Aqua-Shield-1Band: www.medchemexpress.comNovel cell permeable small molecule redulator of specific protein functions The Shield-1 ligand can simultaneously stabilizes and destabilizes a protein of interest depending on the amount of the ligand used within…
n a manner related with LDH release and caspase-3 activation after infection. Similarly, Cif homologue in P. luminescens 1655472 triggers apoptosis in insect cells, albeit this activity is not linked…