vannoortevents | NotchInhibitornotchinhibitor

Caspofungin Acetate

vannoortevents June 22, 2017 0 Comments

Caspofungin AcetateBand: www.medchemexpress.comThe first inhibitor of fungal β-1,3 glucan synthase; Antifungal agent CAS No:179463-17-3 Chemical Name: Cancidas; (4R,5S)-5-((2-aminoethyl)amino)-N(2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide; MK0991 Siponimod Molecular Formula C52H88N10O15 • 2C2H4O2 Molecular Weight 1213.4 CAS…

AZD1080

vannoortevents June 22, 2017 0 Comments

AZD1080Band: www.medchemexpress.comA potent, brain permeable inhibitor of GSK3α and GSK3β (Kis = 6.9 and 31 nM, respectively)CAS No:612487-72-6 Chemical Name: 2-hydroxy-3--1H-indole-5-carbonitrile AZD-9291 Molecular Formula C19H18N4O2 Molecular Weight 334.4 CAS Numbers 612487-72-6…

GN6958

vannoortevents June 22, 2017 0 Comments

GN6958Band: www.medchemexpress.comNon-peptidic selective SUMO-sentrin specific protease (SENP)1 protease inhibitorCAS No: 1392278-32-8 Chemical Name: Ethyl 3-{-methyl}-benzoate MK-1775 Molecular Formula C24H25N3O3 Molecular Weight 403.47 CAS Numbers 1392278-32-8 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18487274

GI254023X

vannoortevents June 22, 2017 0 Comments

GI254023XBand: www.medchemexpress.comADAM10-specific metalloprotease inhibitor, preventing Hla-mediated injury References: 1) Hundhausen et al (2003) The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediates cell-cell adhesion. Blood 102 1186. PMID: 12714508.…

Danoprevir (ITMN191)

vannoortevents June 22, 2017 0 Comments

Danoprevir (ITMN191)Band: www.medchemexpress.comA promising, potent NS3/4A protease inhibitor for the oral treatment of HCV infection.CAS No: 850876-88-9 Chemical Name: (2R,13aS,14aR,16aS,Z)-6-((tert-butoxycarbonyl)amino)-14a-((cyclopropylsulfonyl)carbamoyl)-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropapyrrolodiazacyclopentadecin-2-yl 4-fluoroisoindoline-2-carboxylate VX-765 Molecular Formula C35H46FN5O9S Molecular Weight 731.83 CAS Numbers 850876-88-9…

ARDP0006

vannoortevents June 22, 2017 0 Comments

ARDP0006Band: www.medchemexpress.comNovel NS2B-NS3 protease inhibitor AMG 232 Molecular Formula C14H6N2O8 Molecular Weight 330.21 CAS Numbers 81-55-0 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility DMSO Purity 98%…

ABT-450

vannoortevents June 22, 2017 0 Comments

ABT-450Band: www.medchemexpress.comA potent non-structural protein 3/4A (NS3/4A) protease inhibitor CAS No: 1221573-85-8 (1216941-48-8 ) Reparixin Molecular Formula C40H43N7O7S Molecular Weight 765.87 CAS Numbers 1216941-48-8 Storage Condition 0°C (short term), -20°C (long…

ABT-263

vannoortevents June 22, 2017 0 Comments

ABT-263Band: www.medchemexpress.comA potent, selective and orally bioavailable inhibitor of B-cell lymphoma-2 (BCL-2) family proteinsCAS No:923564-51-6 LY2109761 Molecular Formula C47H55ClF3N5O6S3 Molecular Weight 974.61 CAS Numbers 923564-51-6 Storage Condition 0°C (short term),…

3-MB-PP1

vannoortevents June 22, 2017 0 Comments

3-MB-PP1Band: www.medchemexpress.comHighly ASKA- (analog-sensitive kinase alleles) selective inhibitorCAS No: 956025-83-5 Chemical Name: 1-(tert-Butyl)-3-(3-methylbenzyl)-1H-pyrazolopyrimidin-4-amine; Plk1 ASKA Inhibitor; Syk ASKA Inhibitor; ZAP-70 ASKA Inhibitor; PP1 Analog III Pexidartinib Molecular Formula C17H21N5 Molecular…

2OH-BNPP1

vannoortevents June 22, 2017 0 Comments

2OH-BNPP1Band: www.medchemexpress.comNovel inhibitor of the kinase activity of BUB1CAS No: 833481-73-5 Chemical Name: 2-pyrimidin-3-yl)methyl]phenol Asunaprevir Molecular Formula C16H19N5O Molecular Weight 297.35 CAS Numbers 833481-73-5 Storage Condition 0°C (short term), -20°C (long…

Caspofungin Acetate

AZD1080

GN6958

GI254023X

Danoprevir (ITMN191)

ARDP0006

ABT-450

ABT-263

3-MB-PP1

2OH-BNPP1

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