CLP-290Band: www.medchemexpress.comNovel KCC2 modulator and prodrug of CLP-257, highly selective for KCC2 over related Cl- transportersCAS No: 1181083-81-7 Chemical Name: phenyl] pyrrolidine-1-carboxylate GDC-0032 Molecular Formula C19H21FN4O3S Molecular Weight 404.46 CAS Numbers…
CaCC(inh)-A01Band: www.medchemexpress.comPotent, selective class A inhibitor of calcium-activated chloride channels CAS No: 407587-33-1 Chemical Name: CaCCinh-A01; 6-t-Butyl-2-(furan-2-carboxamido)-4,5,6,7-tetrahydrobenzo thiophene-3-carboxylic Preladenant Molecular Formula C18H21NO4S Molecular Weight 347.43 CAS Numbers 407587-33-1 Storage Condition 0°C (short…
B355252Band: www.medchemexpress.comNovel potentiator of nerve growth factor (NGF)-induced neurite outgrowth, blocking Ca2+ and ROS production, suppressing glutamate-evoked oxidative stress, and altering the phosphorylation states of Erk kinasesCAS No: 1261576-81-1 Chemical Name: 4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide…
DefactinibBand: www.medchemexpress.comA non-receptor tyrosine kinaseCAS No:1073154-85-4 Chemical Name: VS-6063, PF-04554878 Acalabrutinib Molecular Formula C20H21F3N8O3S Molecular Weight 510.5 CAS Numbers 1073154-85-4 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility DMSO…
BMS-599626Band: www.medchemexpress.comAn orally bioavailable pan-HER tyrosine kinase inhibitor. It inhibits human epidermal growth factor receptorsCAS No:8173837-23-1 Chemical Name:AC480 Quisinostat Molecular Formula C27H27FN8O3 Molecular Weight 530.55 CAS Numbers 8173837-23-1 Storage Condition…
AZD9291Band: www.medchemexpress.comAn oral, irreversible, potent and selective third generation tyrosine kinase inhibitor (TKI)CAS No:1421373-65-0 Chemical Name: N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide CH5424802 Molecular Formula C28H33N7O2 Molecular Weight 499.6 CAS Numbers 1421373-65-0 Storage Condition 0°C (short…
AZD4547Band: www.medchemexpress.comA potent, selective and orally active pan-FGFR inhibitorCAS No:1035270-39-3 Selumetinib Molecular Formula C26H33N5O3 Molecular Weight 463.58 CAS Numbers 1035270-39-3 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility…
Auten-99Band: www.medchemexpress.comNovel inhibitor of the myotubularin phosphatase Jumpy (also called MTMR14), acrossing the blood-brain barrier and exerting potent neuroprotective effects CAS No: 1049780-58-6 Chemical Name: Autophagy Enhancer-99; T05128758; 2-Biphenyl-4-yl-5,6-dihydro-imidazothiazole hydrobromide NVP-AUY922…
PF-9184Band: www.medchemexpress.comHighly potent and selective inhibitor of recombinant human microsomal prostaglandin synthase 1 (mPGES-1)CAS No: 1221971-47-6 Chemical Name: N-(3,4-Dichloro-4-yl)-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide Dinaciclib Molecular Formula C21H14Cl2N2O4S Molecular Weight 461.32 CAS Numbers 1221971-47-6…
APO-866 (FK866)Band: www.medchemexpress.comPotent inhibitor of NAMPT against C6 glioblastoma CAS No: 658084-64-1 Chemical Name: FK866; Daporinad; K22.175; (E)-N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide AZD-7762 Molecular Formula C₂₄H₂₉N₃O₂ Molecular Weight 391.51 CAS Numbers 658084-64-1 Storage Condition 0°C…