CYM-5520Band: www.medchemexpress.comNovel allosteric agonist of Sphingosine 1-phosphate receptor 2 (S1PR2)CAS No: 1449747-00-5 Chemical Name: 1--6-oxo-1,6-dihydro-pyridine-3-carbonitrile AZD4547 Molecular Formula C21H19N3O2 Molecular Weight 345.39 CAS Numbers 1449747-00-5 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18490573
CPI-613Band: www.medchemexpress.comAn E1α pyruvate dehydrogenase (PDH) modulator that prevents cancer cells from metabolizing glucose for energy. CPI-613 has been granted orphan drug status by the US FDA for pancreatic cancerCAS…
CLP-290Band: www.medchemexpress.comNovel KCC2 modulator and prodrug of CLP-257, highly selective for KCC2 over related Cl- transportersCAS No: 1181083-81-7 Chemical Name: phenyl] pyrrolidine-1-carboxylate GDC-0032 Molecular Formula C19H21FN4O3S Molecular Weight 404.46 CAS Numbers…
CaCC(inh)-A01Band: www.medchemexpress.comPotent, selective class A inhibitor of calcium-activated chloride channels CAS No: 407587-33-1 Chemical Name: CaCCinh-A01; 6-t-Butyl-2-(furan-2-carboxamido)-4,5,6,7-tetrahydrobenzo thiophene-3-carboxylic Preladenant Molecular Formula C18H21NO4S Molecular Weight 347.43 CAS Numbers 407587-33-1 Storage Condition 0°C (short…
B355252Band: www.medchemexpress.comNovel potentiator of nerve growth factor (NGF)-induced neurite outgrowth, blocking Ca2+ and ROS production, suppressing glutamate-evoked oxidative stress, and altering the phosphorylation states of Erk kinasesCAS No: 1261576-81-1 Chemical Name: 4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide…
DefactinibBand: www.medchemexpress.comA non-receptor tyrosine kinaseCAS No:1073154-85-4 Chemical Name: VS-6063, PF-04554878 Acalabrutinib Molecular Formula C20H21F3N8O3S Molecular Weight 510.5 CAS Numbers 1073154-85-4 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility DMSO…
RepaglinideBand: www.medchemexpress.comPotent short-acting insulin secretagogue, closing ATP-sensitive potassium (KATP) channels CAS No: 135062-02-1 Chemical Name: Prandin; NovoNorm; GlucoNorm; 2-Ethoxy-4-amino]-2-oxoethyl]benzoic acid c-Kit-IN-1 Molecular Formula C27H36N2O4 Molecular Weight 452.6 CAS Numbers 135062-02-1 Storage…
ML077 (VU0255011)Band: www.medchemexpress.comHighly selective, potent, saline soluble, "best in class" KCC2 antagonistCAS No: 1135304-61-8 Chemical Name: N-Methyl-N-(4-methyl-1,3-thiazol-2-yl)-2-(6-phenylpyridazin-3-yl)sulfanylacetamide; ML-077; CID-25067404; VU0255011 Eliglustat Molecular Formula C17H16N4OS2 Molecular Weight 356.47 CAS Numbers 1135304-61-8…
GliquidoneBand: www.medchemexpress.comPotent, second-generation SUR1 ligand, blocking ATP-dependent K+ (KATP) channels and leading to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increasing insulin release CAS No: 33342-05-1 Chemical…
SelamectinBand: www.medchemexpress.comTopical parasiticide and antihelminthicCAS No: 220119-17-5 Chemical Name: (5Z)-25-Cyclohexyl-4′-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)avermectin SRT 2104 Molecular Formula C43H63NO11 Molecular Weight 769.96 CAS Numbers 220119-17-5 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility…