TLR7 agonist T7Band: www.medchemexpress.comNovel Toll-like receptor 7 (TLR7) agonist, eliciting the nonspecific antitumor responses and strengthening the specific humoral and cellular immune responsesCAS No: 1062444-54-5 Chemical Name: 4-methyl]-benzoic acid Birinapant…
Deltarasin HCl saltBand: www.medchemexpress.comA novel small molecule inhibiting the KRAS-PDE interactionCAS No:1440898-82-7 (HCl salt) 1440898-61-2 (Free Base) c-Kit-IN-2 Molecular Formula C40H37N5O 2HCl Molecular Weight 691.3 CAS Numbers 1440898-82-7 (HCl salt)…
MCC950 sodiumBand: www.medchemexpress.comPotent and selective inhibitor of NLRP3, reducing interleukin-1β (IL-1β) production in vivo and attenuating the severity of experimental autoimmune encephalomyelitis (EAE)CAS No: 256373-96-3 (free urea 210826-40-7) Chemical Name: CP-456773…
AuranofinBand: www.medchemexpress.comAntirheumatic agent, inhibiting IL-1ß secretion, suppressing pro-IL-1ß mRNA expression in response to LPS, zymosan and Fusobacterium nucleatum/Peptostreptococcus anaerobius bacterial infection, reducing pro-IL-1ß production in peritoneal cells and RAW 264.7…
APY0201Band: www.medchemexpress.comA potent and selective IL-12/23 inhibitor.CAS No:1232221-74-7 SRT 2105 Molecular Formula C23H23N7O Molecular Weight 413.48 CAS Numbers 1232221-74-7 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility DMSO…
AN2728Band: www.medchemexpress.comA topically administered, boron-containing, anti-inflammatory compound that inhibits PDE4 activity and thereby suppresses the release of TNFalpha, IL-12, IL-23 and other cytokinesCAS No:906673-24-3 INK-129 Molecular Formula C14H10BNO3 Molecular Weight…
TFMB-(R)-2-HGBand: www.medchemexpress.comCell membrane-permeable version of (R)-2-HG as a promoter of leukemogenesis, dose-dependently and passage-dependently blocking differentiationCAS No: 1445700-01-5 Chemical Name: (2R)-Tetrahydro-5-oxo-2-furancarboxylic acid methyl ester GSK344 Molecular Formula C13H11F3O4 Molecular Weight 288.22…
MEK162 (Arry-162)Band: www.medchemexpress.comPotent, orally bioavailable and non-ATP competitive inhibitor of MEK1 and MEK2CAS No:606143-89-9 Chemical Name: Binimetinib, MEK162 Bindarit Molecular Formula C17H15BrF2N4O3 Molecular Weight 441.23 CAS Numbers 606143-89-9 Storage Condition 0°C…
Adenosine N1-oxideBand: www.medchemexpress.comInhibitor of secretion of inflammatory mediators, suppressing pro-inflammatory cytokine secretionCAS No:146-92-9 Chemical Name: ANO; Adenosine, 1-oxide; (2R,3R,4S,5R)-2-(1-Hydroxy-6-iminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol Tipifarnib Molecular Formula C10H13N5O5 Molecular Weight 283.24 CAS Numbers 146-92-9 Storage Condition…
WZ-811Band: www.medchemexpress.comPotent chemokine receptor type 4 (CXCR4) antagonist CAS No: 55778-02-4 Chemical Name: N1,N4-Di-2-pyridinyl-1,4-benzenedimethanamine E-3811 Molecular Formula C18H18N4 Molecular Weight 290.36 CAS Numbers 55778-02-4 Storage Condition 0°C (short term), -20°C (long…