Tly made use of [1]. This antimicrobial was initially classified as an antiparasitic agent as a result of its activity against Taenia saginata and Hymenolepis nana. After that, a higher spectrum was discussed, provided the discovery of its antimicrobial activity against Enterobacteriaceae, Trichomonas vaginalis, Entamoeba histolytica, and Clostridium difficile. Nitazoxanide was deemed an essential therapeutic drug in metronidazole-resistant circumstances. In addition to that, the spectrum of nitazoxanide also involves activity against viral CC-115 (hydrochloride) supplier ailments for example hepatitis C. At the moment, nitazoxanide is definitely an essential selection to treat Cryptosporidium and Giardia infections, that are vital etiologies of diarrhea in the pediatric population in establishing countries, at the same time as in immunocompromised patients. Nitazoxanide can also be an option therapy for Clostridium difficile diarrhea in inpatients [2-6]. Also towards the above uses, recent studies have discovered a promising anticancer effect of nitazoxanide, which could have a major impact on public overall health [7-8]. Nitazoxanide is a drug that preserves its spectrum and this has come to be as an essential therapeutic tool, so it demands a lot more investigation on potential future therapeutic effects [9]. Then, the objective of this study was to assess the scientific production of nitazoxanide in 4 international bibliographical databases.Materials And MethodsA bibliometric study in regards to the international scientific production on nitazoxanide was carried out. This assessment was performed in four significant regional and international bibliographical databases, two of them in English and two in Spanish: Index MedicusMedlinePubMed (www.pubmed.com) (English), analyzed through the GoPubMed(http:gopubmed.comwebgopubmed) (January 1809-April 2017), Scopus (https:www.scopus.com) from Elsevier (January 1959-April 2017) (English), SciELO (integrated) (http:scielo.orgphpindex.php) (2004-2016) (Spanish) and LILACS (Latin American Literature on Well being Sciences) (http:lilacs.bvsalud.orges) (1980-2016) (Spanish). All of the regions with the world, also as registered countries inside the databases, had been searched. As these databases have distinctive literature coverage, benefits are presented per database, because of the fact 
that it really is not technically possible to integrate them, as they are not with the exact same top quality too, amongst other limitations. This analysis strategy employed the following keyword phrases (MeSH, Health-related Topic Headings): “Nitazoxanide (nitazoxanide)” AND “Argentina”, “Nitazoxanide (nitazoxanide)” AND “Zimbabwe” and inside the exact same way because the rest of nations. We determined the quantity, excellent (express because the quantity of citations, much more of them additional relative high-quality), and varieties of research performed by every single country, characterizing them for many years, international cooperation (IC), nation of publication (COP), citations and H-index, authors and groups with all the highest contribution. Information was tabulated and analyzed in Excel 365for Windows eight summarizing quantitative2017 Rodriguez-Morales et al. Cureus 9(five): e1204. DOI 10.7759cureus.2 ofvariables with implies and standard deviations ( E) and qualitative with proportions.ResultsMedlineIn Medline, we discovered 512 articles published and indexed in the study period, having a clear trend to enhance their analysis within the last decade (Figure 1).FIGURE 1: Evolution over time of publication PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21344248 on nitazoxanide in MedlineAnalyzing the results by planet regions, Europe leads scientific analysis on nitazoxanide, followed by North America with all the lar.