Name :
Biotinylated Anti-IGF-1R antibody(DMC721), IgG1 Chimeric mAb
Uniprot ID :
P08069
Common Name :
Synonyms :
CD221; IGFIR; IGFR; JTK13
Application :
Flow Cyt
Recommended Dilutions :
Flow Cyt 1/100
Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Host Species :
Rabbit
IgG type :
Rabbit/Human Fc chimeric IgG1
Reactivity :
Human
Target :
IGF-1R
Description :
Anti-IGF-1R antibody(DMC721); IgG1 Chimeric mAb
Delivery :
2-3 weeks
Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background :
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Usage :
Research use only
Related websites: https://www.medchemexpress.com/antibodies.html
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