Name :
Biotinylated Anti-GITR antibody(DM80); Rabbit mAb
Uniprot ID :
Q9Y5U5
Common Name :
Synonyms :
AITR; GITR; TNFRSF18; CD357
Application :
ELISA; Flow Cyt
Recommended Dilutions :
ELISA 1:5000-10000; Flow Cyt 1:100
Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Host Species :
Rabbit
IgG type :
Rabbit IgG
Reactivity :
Human
Target :
GITR
Description :
Biotinylated Anti-GITR antibody(DM80); Rabbit mAb
Delivery :
2-3 weeks
Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background :
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation; and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25( )CD4( ) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Usage :
Research use only
Related websites: https://www.medchemexpress.com/antibodies.html
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