Name :
Biotinylated Anti-FGFR4 antibody(DMC460), IgG1 Chimeric mAb
Uniprot ID :
P22455
Common Name :
Synonyms :
CD334; JTK2; TKF
Application :
Flow Cyt
Recommended Dilutions :
Flow Cyt 1:100
Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Host Species :
Rabbit
IgG type :
Rabbit/Human Fc chimeric IgG1
Reactivity :
Human
Target :
FGFR4
Description :
Anti-FGFR4 antibody(DMC460); IgG1 Chimeric mAb
Delivery :
2-3 weeks
Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background :
The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways; including cell proliferation; cell differentiation; cell migration; lipid metabolism; bile acid biosynthesis; vitamin D metabolism; glucose uptake; and phosphate homeostasis. This protein consists of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment; and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation. [provided by RefSeq; Aug 2017]
Usage :
Research use only
Related websites: https://www.medchemexpress.com/antibodies.html
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