Name :
Biotinylated Anti-Dxd antibody(1A5); Rabbit mAb
Uniprot ID :
N.A.
Common Name :
Synonyms :
N.A.
Application :
ELISA
Recommended Dilutions :
ELISA 1:5000-10000
Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Host Species :
Rabbit
IgG type :
Rabbit IgG
Reactivity :
N.A.
Target :
Dxd
Description :
Anti-Dxd antibody(1A5); Rabbit mAb
Delivery :
2-3 weeks
Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background :
Dxd is a potent anti-cancer drug, acting as an alkaloid camptothecin analog and a DNA topoisomerase I inhibitor. It forms a stable complex with topoisomerase I and DNA, impeding DNA replication and inducing cancer cell death. Dxd is utilized as a payload in specific antibody-drug conjugates (ADCs), with examples such as trastuzumab deruxtecan targeting HER2 and patritumab deruxtecan targeting HER3.
Usage :
Research use only
Related websites: https://www.medchemexpress.com/antibodies.html
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