Thu. Dec 26th, 2024

Name :
Biotinylated Anti-DDR1 antibody(DMC480); IgG1 Chimeric mAb

Uniprot ID :
Q08345

Common Name :

Synonyms :
CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE; MCK-10; HGK2; CD167a

Application :
Flow Cyt

Recommended Dilutions :
Flow Cyt 1:100

Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Host Species :
Rabbit

IgG type :
Rabbit/Human Fc chimeric IgG1

Reactivity :
Human

Target :
DDR1

Description :
Anti-DDR1 antibody(DMC480); IgG1 Chimeric mAb

Delivery :
2-3 weeks

Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Background :
Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth; differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain; and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells; particularly in the kidney; lung; gastrointestinal tract; and brain. In addition; it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq; Feb 2011]

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Usage :
Research use only

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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