Fri. Nov 1st, 2024

Name :
Biotinylated Anti-CCR4 antibody(DMC297); IgG1 Chimeric mAb

Uniprot ID :
P51679

Common Name :

Synonyms :
CC-CKR-4; CD194; ChemR13; CKR4; CMKBR4; HGCN:14099; K5-5

Application :
Flow Cyt

Recommended Dilutions :
Flow Cyt 1:100

Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Host Species :
Rabbit

IgG type :
Rabbit/Human Fc chimeric IgG1

Reactivity :
Human

Target :
CCR4

Description :
Anti-CCR4 antibody(DMC297); IgG1 Chimeric mAb

Delivery :
2-3 weeks

Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Background :
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine – MIP-1; RANTES; TARC and MCP-1. Chemokines are a group of small polypeptide; structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development; homeostasis; and function of the immune system; and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

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Usage :
Research use only

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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