Sat. Dec 21st, 2024

Name :
Anti-HBEGF antibody(DMC500); IgG1 Chimeric mAb

Uniprot ID :
Q99075

Common Name :

Synonyms :
DTR; DTS; DTSF; HEGFL

Application :
Flow Cyt

Recommended Dilutions :
Flow Cyt 1:100

Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Host Species :
Rabbit

IgG type :
Rabbit/Human Fc chimeric IgG1

Reactivity :
Human

Target :
HBEGF

Description :
Anti-HBEGF antibody(DMC500); IgG1 Chimeric mAb

Delivery :
In Stock

Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Background :
Growth factor that mediates its effects via EGFR; ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts; but not endothelial cells. It is able to bind EGF receptor:EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB:Swiss-Prot Function]

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Usage :
Research use only

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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