Name :
Anti-CD45 antibody(DM193); Rabbit mAb
Uniprot ID :
P08575
Common Name :
Synonyms :
B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200
Application :
ELISA; Flow Cyt
Recommended Dilutions :
ELISA 1:5000-10000; Flow Cyt 1:100
Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Host Species :
Rabbit
IgG type :
Rabbit IgG
Reactivity :
Human
Target :
CD45
Description :
Anti-CD45 antibody(DM193); Rabbit mAb
Delivery :
In Stock
Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background :
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitosis; and oncogenic transformation. This PTP contains an extracellular domain; a single transmembrane segment and two tandem intracytoplasmic catalytic domains; and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes; or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases; and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene; which encode distinct isoforms; have been reported.
Usage :
Research use only
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
ATF6 Antibody (YA604)
HRP-conjugated AffiniPure Goat Anti-Rabbit IgG H&L
Phospho-ERK1/2 (Tyr204/Tyr187) Antibody: Phospho-ERK1/2 (Tyr204/Tyr187) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 42,44 kDa, targeting to Phospho-ERK1/2 (Tyr204/Tyr187). It can be used for WB,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.