Name :
Biotinylated Anti-NKG2A antibody(DMC298); IgG1 Chimeric mAb
Uniprot ID :
P26715
Common Name :
Synonyms :
CD159A; NKG2; NKG2A
Application :
Flow Cyt
Recommended Dilutions :
Flow Cyt 1:100
Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Host Species :
Rabbit
IgG type :
Rabbit/Human Fc chimeric IgG1
Reactivity :
Human
Target :
NKG2A
Description :
Anti-NKG2A antibody(DMC298); IgG1 Chimeric mAb
Delivery :
2-3 weeks
Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background :
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family; also called NKG2 family; which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member; KLRD1:CD94; and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Usage :
Research use only
Related websites: https://www.medchemexpress.com/antibodies.html
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