Name :
Biotinylated Anti-GPNMB antibody(11G4), IgG1 Chimeric mAb
Uniprot ID :
Q14956
Common Name :
Synonyms :
HGFIN;NMB;PLCA3
Application :
Flow Cyt
Recommended Dilutions :
Flow Cyt 1/100
Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Host Species :
Rabbit
IgG type :
Rabbit/Human Fc chimeric IgG1
Reactivity :
Human
Target :
GPNMB
Description :
Anti-GPNMB antibody(11G4), IgG1 Chimeric mAb
Delivery :
2-3 weeks
Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background :
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Usage :
Research use only
Related websites: https://www.medchemexpress.com/antibodies.html
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