Name :
Anti-CTLA-4 antibody(DM51); Rabbit mAb
Uniprot ID :
P16410
Common Name :
Synonyms :
CTLA4; CD152
Application :
ELISA; Flow Cyt
Recommended Dilutions :
ELISA 1:5000-10000; Flow Cyt 1:100
Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Host Species :
Rabbit
IgG type :
Rabbit IgG
Reactivity :
Human
Target :
CTLA-4
Description :
Anti-CTLA-4 antibody(DM51); Rabbit mAb
Delivery :
In Stock
Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background :
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain; a transmembrane domain; and a cytoplasmic tail. Alternate transcriptional splice variants; encoding different isoforms; have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond; while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus; Graves disease; Hashimoto thyroiditis; celiac disease; systemic lupus erythematosus; thyroid-associated orbitopathy; and other autoimmune diseases.
Usage :
Research use only
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Phospho-p53 (Ser392) Antibody
MAP2 Antibody
SOCS2 Antibody: SOCS2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 22 kDa, targeting to SOCS2. It can be used for WB,ICC,IF,IP,IHC-P assays with tag free, in the background of Human.