Sun. Sep 8th, 2024

Name :
Anti-CD70 antibody(DM191); Rabbit mAb

Uniprot ID :
P32970

Common Name :

Synonyms :
CD70;CD27LG;TNFSF7;TNFSF7G;CD27L

Application :
ELISA; Flow Cyt

Recommended Dilutions :
ELISA 1:5000-10000; Flow Cyt 1:100

Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Host Species :
Rabbit

IgG type :
Rabbit IgG

Reactivity :
Human

Target :
CD70

Description :
Anti-CD70 antibody(DM191); Rabbit mAb

Delivery :
In Stock

Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Background :
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27:CD27. It is a surface antigen on activated; but not on resting; T and B lymphocytes. It induces proliferation of costimulated T cells; enhances the generation of cytolytic T cells; and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation; cytotoxic function of natural killer cells; and immunoglobulin sythesis.

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Usage :
Research use only

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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