microbiota and their metabolic output is poorly studied. We also chose rice as a handle to help us confirm the prebiotic nature of oats, modulating the gut microbiota and mediating a wellness impact compared with an equivalent, nonprebiotic cereal. We think that this real-world predicament provides a stronger demonstration both on the advantage of oats in normalizing blood lipid profiles inFrontiers in Immunology | frontiersin.orgDecember 2021 | Volume 12 | ArticleXu et al.Hypolipidaemic Impact of Oathypercholesterolemic subjects and in mediating a prebiotic modulation from the gut microbiota. A further limitation is that, the relationships amongst blood lipids, gut microbiota, and SCFAs had been concluded from the statistical process of correlation analysis only, which might not be trustworthy but supply new clues for our next experiments aiming to explore the causal relationships via fecal microbiota transplantation technology. Lastly, we weren’t able to get the fecal samples from the participants in the Beijing website, resulting in a fairly little sample size for metagenomics evaluation. Bcl-2 Activator MedChemExpress Larger sample size with well-designed trials is expected to get further evidence.and was offered a favorable ethics evaluation and approved by the China Ethics Committee of Registering CYP3 Activator supplier Clinical Trials (ChiECRCT-20180139). The patients/participants provided their written informed consent to take part in this study.AUTHOR CONTRIBUTIONSConception and design and style in the study: GS, YY, and DX. Experiment execution: DX, SW, DP, HL and JS. Collection of data: SW, DP, HL and JS. Analysis and interpretation of information: MF, YC, FL, XY, CY, BZ, NL, XW, QX. Drafting in the manuscript: DX, YC, XZ, KT, VS. Important revision of the manuscript: MF, VS, KT, AK. Administrative assistance and study supervision: GS, YY and JS. All authors contributed to the post and approved the submitted version.5 CONCLUSIONIn summary, our study demonstrated that oats exhibited prebiotic activity and capacity of oats to modulate microbiota showed a preliminary causal partnership with its cholesterollowering capability in mild hypercholesterolemic people.FUNDING Information AVAILABILITY STATEMENTThe raw metagenommics sequence information have been deposited into the National Microbiology Information Center (nmdc.cn), plus the accession quantity is NMDC40012570; other data that support the findings of this study are obtainable in the corresponding author upon affordable request. The project was funded by the Chinese Nutrition Society and PepsiCo, Inc., China. The founders play no role in the conduction from the trial. The funds received for open access publication costs are from our institution.SUPPLEMENTARY MATERIAL ETHICS STATEMENTThe studies involving human participants had been reviewed and authorized by the Chinese Clinical Trial Registry (chictr.org.cn) The Supplementary Material for this article can be located on the internet at: frontiersin.org/articles/10.3389/fimmu.2021.787797/ full#supplementary-material
J Bone Metab 2021;28(four):279-296 doi.org/10.11005/jbm.2021.28.four.279 pISSN 2287-6375 eISSN 2287-Review ArticleMedication Associated Osteonecrosis with the Jaw: 2021 Position Statement in the Korean Society for Bone and Mineral Study as well as the Korean Association of Oral and Maxillofacial SurgeonsJin-Woo Kim1,, Mi Kyung Kwak2,, Jeong Joon Han3, Sung-Tak Lee4, Ha Young Kim5, Se Hwa Kim6, Junho Jung7, Jeong Keun Lee8, Young-Kyun Lee9, Yong-Dae Kwon7,, Deog-Yoon Kim10,Department of Oral and Maxillofacial Surgery, School of Medicine, Ewha Womans Un