Ed as 883 g/mol based on the chemical formula for 1: C
Ed as 883 g/mol according to the chemical formula for 1: C46 H74 O16 . The HGS content material of the fruit peel on a dry weight basis was estimated by dividing the content material of HGS inside the samples by the weight with the dried peel samples. Methanol and ammonium bicarbonate have been purchased from Sigma-Aldrich (Tokyo, Japan). 5. Conclusions MPP decreased BW, visceral fat weight, hepatic lipid content, and serum TG levels in HFD-fed rats, possibly due to the HGS content from the peel powder. The in vitro information suggest that these anti-obesity effects of MPP had been partly mediated by the inhibition of intestinal lipid absorption, as demonstrated employing a Chlortoluron References Caco-2 monolayer. For that reason, MPP holds prospective as a meals ingredient with an anti-obesity effect, though a security evaluation continues to be expected.Molecules 2021, 26,15 ofSupplementary Components: The following are obtainable on the net. Figure S1: Matoa peel extract does not suppress oleic acid (OA)-induced lipid accumulation in HuH-7 cells. Figure S2: Chemical structure and data for 3-O-[-L-arabinofuranosyl(13)–L-rhamnopyranosyl(12)–L-arabinopyranosyl] hederagenin (1). Author Contributions: Conceptualization, T.S. and J.N.; Methodology, T.S. and N.K.; Validation, T.S., M.N., N.K., S.T. and J.N.; Formal evaluation, T.S. and N.K.; Investigation, T.S., M.N, N.K. and S.T.; Sources, M.N., N.K. and N.; Information curation, T.S., M.N. and N.K.; Writing riginal Draft Preparation, T.S. and N.K.; Writing eview editing, T.S., M.N., N.K., S.T., N. and J.N.; Visualization, T.S. and N.K.; Supervision, J.N.; Project Administration, T.S. and M.N.; Funding Acquisition: T.S. All authors have read and agreed to the published version from the manuscript. Funding: This study was supported by the Wayo Women’s University Fund for Study (T.S.). Institutional Review Board Statement: The experimental protocol for the care and use of animals was carried out according to the ethical norms authorized by the Animal Care and Use Committee of Wayo Women’s University (Ethical approval quantity: 1801 and 1901). Informed Consent Statement: Not applicable. Information Availability Statement: The data that support the findings of this study are obtainable from the corresponding authors upon affordable request. Acknowledgments: The authors would prefer to thank Y. Yoshida and C. Miyazaki for technical help with all the experimental determination of fecal TG content. Conflicts of Interest: The authors declare no conflict of interest. Sample Availability: Samples from the compounds will not be available from the authors.
moleculesArticleAttenuative Effects of Fluoxetine and Triticum aestivum against Aluminum-Induced Alzheimer’s Disease in Rats: The Doable Consequences on Hepatotoxicity and NephrotoxicityKarema Abu-Elfotuh 1 , Ghada M. Ragab 2 , Ahmad Salahuddin 3, , Lubna Jamil 4 and Ekram Nemr Abd Al Haleem3Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Cairo 11754, Egypt; [email protected] (K.A.-E.); [email protected] (E.N.A.A.H.) Division of Pharmacology and Toxicology, Faculty of Pharmacy, Misr University for Science and Technology, Giza 12585, Egypt; [email protected] Division of Biochemistry, Faculty of Pharmacy, Damanhour University, Damanhour 22511, Egypt Division of Histology, Faculty of Medicine, October 6 University, Giza 12585, Egypt; [email protected] Correspondence: [email protected]; Tel.: +20-100-518-Citation: Abu-Elfotuh, K.; Ragab, G.M.; Salahuddin, A.; Jamil.