RucaparibBand: www.medchemexpress.comPotent, orally available inhibitor of poly ADP-ribose polymerase (PARP) 1 and 2 CAS No: 283173-50-2 Chemical Name: PF-01367338; 8-Fluoro-2-(4-methylaminomethyl-phenyl)-1,3,4,5-tetrahydro-azepinoindol-6-one LY2835228 Molecular Formula C19H18FN3O Molecular Weight 323.4 CAS Numbers 283173-50-2 Storage…
RomidepsinBand: www.medchemexpress.comAn inhibitor of HDAC (Histone Deacetylases)CAS No:128517-07-7 Chemical Name: FK228, Depsipeptide, FR901228 Monomethyl auristatin E Molecular Formula C24H36N4O6S2 Molecular Weight 540.7 CAS Numbers 128517-07-7 Storage Condition 0°C (short term), -20°C…
RGFP966Band: www.medchemexpress.comThe first-in-class selective inhibitor of histone deacetylase 3 (HDAC3) CAS No: 1396841-57-8 Chemical Name: (E)-N-(2-Amino-4-fluorophenyl)-3-pyrazol-4-yl]prop-2-enamide EPZ015675 Molecular Formula C₂₁H₁₉FN₄O Molecular Weight 362.4 CAS Numbers 1357389-11-7 Storage Condition 0°C (short term),…
RG7422Band: www.medchemexpress.comA selective, dual PI3 Kinase and mTOR Kinase inhibitorCAS No:1032754-93-0 PKC421 Molecular Formula C23H30N8O3S Molecular Weight 498.6 CAS Numbers 1032754-93-0 Storage Condition 0°C (short term), -20°C (long term), desiccated…
Remodelin hydrobromideBand: www.medchemexpress.comA novel potent and selective inhibitor of the acetyl-transferase protein NAT10 Reference: 1) Larrieu D, et al. Chemical inhibition of NAT10 corrects defects of laminopathic cells, Science 344:527-32 (2014)CAS No: 949912-58-7 (free…
R306465 ( JNJ-16241199,)Band: www.medchemexpress.comA novel hydroxamate-based histone deacetylase (HDAC) inhibitor with broad-spectrum antitumour activity against solid and haematological malignancies in preclinical modelsCAS No:604769-01-9 Rigosertib (sodium) Molecular Formula C19H19N5O4S Molecular Weight 413.11…
QuizartinibBand: www.medchemexpress.comA second-generation FLT3 inhibitor that has shown promising activity in AML in Phase II clinical trialsCAS No:950769-58-1 AC220 PF-2545928 Molecular Formula C29H32N6O4S Molecular Weight 560.67 CAS Numbers 950769-58-1 Storage…
PU139Band: www.medchemexpress.comNovel histone acetyltransferase (HAT) inhibitorCAS No: 158093-65-3 Chemical Name: PU-139; 2-(4-Fluorophenyl)isothiazolopyridin-3(2H)-one SCR15 Molecular Formula H12H7FN2OS Molecular Weight 246.26 CAS Numbers 158093-65-3 Storage Condition 0°C (short term), -20°C (long term), desiccated…
Pracinostat (SB939)Band: www.medchemexpress.comA potent pan-HDAC inhibitor CAS No:929016-96-6 ARRY-528 Molecular Formula C₂₀H₃₀N₄O₂ Molecular Weight 358.48 CAS Numbers 929016-96-6 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility DMSO Purity 98%…
PP242Band: www.medchemexpress.comCAS No:1092351-67-1 CP-673459 Molecular Formula C16H16N6O Molecular Weight 308.34 CAS Numbers 1092351-67-1 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility DMSO Purity 98% by HPLC References PubMed…