Sun. Jan 26th, 2025

FK228

FK228Band: www.medchemexpress.comPotent histone deacetylase inhibitorCAS: 128517-07-7   Chemical Name: Romidepsin; (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-diisopropyl-2-oxa-12,13-​dithia-5,8,20,23-tetrazabicyclo                               tricos-16-ene-3,6,9,19,22-p​entone; FK228; FR901228; Chromadax; Depsipeptide Eliglustat Molecular Formula C24H36N4O6S2 Molecular Weight 540.70 CAS Numbers 128517-07-7 Storage Condition 0°C (short term),…

EX-527

EX-527Band: www.medchemexpress.comSelective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members CAS No:49843-98-3 Chemical Name: 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide AVE 0999 Molecular Formula C13H13ClN2O Molecular Weight 248.71 CAS…

EPZ005687

EPZ005687Band: www.medchemexpress.comA potent and selective small molecule inhibitor of histone methyltransferase EZH2CAS No:1396772-26-1 SRT 2112 Molecular Formula C32H37N5O3 Molecular Weight 539.67 CAS Numbers 1396772-26-1 Storage Condition 0°C (short term), -20°C…

EPZ-6438

EPZ-6438Band: www.medchemexpress.comAn orally bioactive, potent, selective and S-adenosyl methionine (SAM) competitive inhibitor of Histone Methyltransferase (HMT) EZH2 References: S. K. Knutson, et al., Durable tumor regression in genetically altered malignant…

Eggmanone

EggmanoneBand: www.medchemexpress.comNovel Hedgehog Inhibitor, Exerting Its Hh-Inhibitory Effects Downstream of SmoCAS No: 505068-32-6 Chemical Name: Egm; 3-(2-Methylallyl)-2-((2-oxo-2-(thiophen-2-yl)ethyl)thio)-5,6,7,8-tetrahydrobenzothienopyrimidine-4(3H)-one GSK351 Molecular Formula C20H20N2O2S3 Molecular Weight 416.58 CAS Numbers 505068-32-6 Storage Condition 0°C (short term),…

DG-172 dihydrochloride

DG-172 dihydrochlorideBand: www.medchemexpress.comOrally available potent PPARß/d inverse agonist, inhibiting Angptl4 gene expression and augmenting GM-CSF/IL-4-induced differentiation of mature dendritic cells from bone marrow cells in cultureCAS No: 1361504-77-9   Chemical Name: DG172…

dBET1

dBET1Band: www.medchemexpress.comNovel competitive antagonist of BET bromodomains to hijack the Cereblon E3 ubiquitin ligase complexCAS No: 1799711-21-9   Chemical Name: JQ1-Thalidomide conjugate; 2(S)-azulen-6-yl]-N-(4-{2--acetylamino}-butyl)-acetamide Tipifarnib Molecular Formula C38H37ClN8O7S Molecular Weight 785.27 CAS Numbers…

Daunorubicin hydrochloride

Daunorubicin hydrochlorideBand: www.medchemexpress.comAntineoplastic antibiotic, inhibiting DNA replication and repair and RNA and protein synthesisCAS No:23541-50-6 Chemical Name: Rubidomycin hydrochloride; Daunorubicinol hydrochloride; (7S,9S)-9-Acetyl-7-oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride E-3818 Molecular Formula C27H29NO10 • HCl Molecular Weight 564.0…

CX-5461

CX-5461Band: www.medchemexpress.comVery potent inhibitor, with an IC50 of less than 10 nM for VEGFR2, MET, Kit and FLT3-ITDCAS No:1138549-36-6 Otamixaban Molecular Formula C27H27N7O2S Molecular Weight 513.61 CAS Numbers 1138549-36-6 Storage…

CUDC-305

CUDC-305Band: www.medchemexpress.comAn orally bioavailable inhibitor of Heat Shock ProteinsCAS No:1061318-81-7 LDK386 Molecular Formula C22H30N6O2S Molecular Weight 442.58 CAS Numbers 1061318-81-7 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility…