EPZ-6438
Band: www.medchemexpress.com
An orally bioactive, potent, selective and S-adenosyl methionine (SAM) competitive inhibitor of Histone Methyltransferase (HMT) EZH2
References:
S. K. Knutson, et al., Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2. Proc Natl Acad Sci U S A. 2013 May 7, 110(19), 7922-7