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Moreover, experienced GPR552/2 mice were being also characterised by significant myocardial remodelling which includes reductions in left ventricular totally free wall thickness, HW:BW and ventricular cell amount, and improved collagen deposition

In conditions of load-dependent cardiovascular variables, each indices of systolic and diastolic purpose were being appreciably altered with age in both WT and GPR552/2 mice (Table one). In unique, ESP,…